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Olopatadine N-Oxide_Molecular_structure_CAS_203188-31-2)
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Olopatadine N-Oxide

Catalog No. O575010 Name Toronto Research Chemicals
CAS Number 203188-31-2 Website http://www.trc-canada.com
M. F. C21H23NO4 Telephone +1 (416) 665-9696
M. W. 353.41162 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 175878

SYNONYMS

IUPAC name
3-[(2Z)-5-(carboxymethyl)-9-oxatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]-N,N-dimethylpropanamine oxide
IUPAC Traditional name
3-[(2Z)-5-(carboxymethyl)-9-oxatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]-N,N-dimethylpropanamine oxide
Synonyms
11-[3-(Dimethyloxidoamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic Acid

DATABASE IDS

CAS Number 203188-31-2

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 155-157°C
Solubility Methanol
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
A metabolite of Olopatadine (M3). A dibenz[b,e]oxepin derivative as antiallergic agents, useful for treatment of asthma, allergic rhinitis, atopic dermatitis.

REFERENCES

  • Mizuno, N., et al.: Drug Metabol. Pharmacokin., 17, 93 (2002)
  • Polli, J., et al.: J. Pharm. Sci., 92, 2082 (2002)
  • Tashiro, M., et al.: J. Clin. Pharmacol., 44, 890 (2002)
  • Ohashi, R., et al.: Drug Metab. Disos., 34, 793 (2002)