Olopatadine N-Oxide

• Catalog No.: O575010
• CAS Number: 203188-31-2
• M. F.: C21H23NO4
• M. W.: 353.41162
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 3-[(2Z)-5-(carboxymethyl)-9-oxatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]-N,N-dimethylpropanamine oxide
• IUPAC Traditional name: 3-[(2Z)-5-(carboxymethyl)-9-oxatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]-N,N-dimethylpropanamine oxide
• Synonyms: 11-[3-(Dimethyloxidoamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic Acid

DATABASE IDS

• CAS Number: 203188-31-2

PROPERTIES

• Apperance: White Solid
• Melting Point: 155-157°C
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Olopatadine (M3). A dibenz[b,e]oxepin derivative as antiallergic agents, useful for treatment of asthma, allergic rhinitis, atopic dermatitis.

REFERENCES

• Mizuno, N., et al.: Drug Metabol. Pharmacokin., 17, 93 (2002)
• Polli, J., et al.: J. Pharm. Sci., 92, 2082 (2002)
• Tashiro, M., et al.: J. Clin. Pharmacol., 44, 890 (2002)
• Ohashi, R., et al.: Drug Metab. Disos., 34, 793 (2002)