Olopatadine-d3 Hydrochloride

• Catalog No.: O575002
• M. F.: C21H24ClNO3
• M. W.: 373.87316
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 2-[(2Z)-2-{3-[(^2H₃)methyl(methyl)amino]propylidene}-9-oxatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-5-yl]acetic acid hydrochloride
• IUPAC Traditional name: [(2Z)-2-{3-[(^2H₃)methyl(methyl)amino]propylidene}-9-oxatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-5-yl]acetic acid hydrochloride
• Synonyms: Opatanol-d3; Allelock-d3; (11Z)-11-[3-(Dimethyl-d3-amino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic Acid Hydrochloride; Patanol-d3; KW 4679-d3; ALO 4943A-d3

PROPERTIES

• Apperance: Pale Grey Solid
• Melting Point: 230-234°C (dec.)
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Refrigerator

DETAILS

Description (English)

Labelled Olopatadine. Dual acting histamine H1-receptor antagonist and mast cell stabilizer. Antiallergic; antihistaminic.

REFERENCES

• Kamei, C., et al.: Arzneim.-Forsch., 45, 1005 (1995)
• Sharif, N.A., et al.: J. Pharmacol. Exp. Ther., 278, 1252 (1995)
• Abelson, M.B., et al.: Am. J. Ophthalmol., 125, 797 (1995)