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Olanzapine Lactam Impurity

Catalog No. O253765 Name Toronto Research Chemicals
CAS Number 1017241-34-7 Website http://www.trc-canada.com
M. F. C17H20N4O2 Telephone +1 (416) 665-9696
M. W. 312.3663 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 175818

SYNONYMS

IUPAC name
(3Z)-4-(4-methylpiperazin-1-yl)-3-(2-oxopropylidene)-2,3-dihydro-1H-1,5-benzodiazepin-2-one
IUPAC Traditional name
(3Z)-4-(4-methylpiperazin-1-yl)-3-(2-oxopropylidene)-1H-1,5-benzodiazepin-2-one
Synonyms
(3Z)-1,3-Dihydro-4-(4-methyl-1-piperazinyl)-3-(2-oxopropylidene)-2H-1,5-benzodiazepin-2-one

DATABASE IDS

CAS Number 1017241-34-7

PROPERTIES

Certificate of Analysis Download
Apperance Yellow Solid
Melting Point 188-191°C (dec.)
Solubility DMSO
Solubility Warm Methanol
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
A degradation product of Olanzapine (LY170053) (O253750) in solid oral formulations.

REFERENCES

  • Chakrabarti, J., et al.: J.Med. Chem., 25, 1133 (1982)
  • Chafetz, L., et al.: J. Pharm. Sci., 73, 1186 (1982)
  • Hartauer, K., et al.: Pharm. Dev. Technol., 5, 303 (1982)