Octreotide-phenylalanine-d8 di-Trifluoroacetic Acid Salt

• Catalog No.: O239952
• M. F.: C49H66N10O10S2
• M. W.: 1019.23934

SYNONYMS

• IUPAC name: 19-[2-amino-3-(^2H₅)phenyl(^2H₃)propanamido]-10-(4-aminobutyl)-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
• IUPAC Traditional name: 19-[2-amino-3-(^2H₅)phenyl(^2H₃)propanamido]-10-(4-aminobutyl)-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
• Synonyms: D-(Phenylalanyl-d8)-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide Cyclic (2-7)-Disulfide di-Trifluoroacetic Acid Salt; Sandostatin-d8 di-Trifluoroacetic Acid Salt; SMS 201-995-d8 di-Trifluoroacetic Acid Salt; Sandostatin LAR-d8 di-Trifluoroacetic Acid Salt

DETAILS

Description (English)

Labelled octapeptide analog of Somatostatin. A gastric antisecretory agent. Used in treatment of acromegaly.

REFERENCES

• Bauer, W., et al.: Life Sci., 31, 1133 (1982)
• Plewe, G., et al.: Lancet, 2, 782 (1982)
• Kraenzlin, M.E., et al.: Experientia, 41, 738 (1982)
• del Pozo, E., et al.: Acta Endocrinol., 111, 433 (1982)