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Ochromycinone

Catalog No. O150000 Name Toronto Research Chemicals
CAS Number 28882-53-3 Website http://www.trc-canada.com
M. F. C19H14O4 Telephone +1 (416) 665-9696
M. W. 306.31206 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Amber Vial, -20°C Freezer Chembase ID: 175759

SYNONYMS

IUPAC name
(3S)-8-hydroxy-3-methyl-1,2,3,4,7,12-hexahydrotetraphene-1,7,12-trione
IUPAC Traditional name
(3S)-8-hydroxy-3-methyl-3,4-dihydro-2H-tetraphene-1,7,12-trione
Synonyms
(S)-Ochromycinone, (+)-Ochromycinone, Deoxytetrangomycin, STA-21(3S)-3,4-Dihydro-8-hydroxy-3-methyl-Benz[a]anthracene-1,7,12(2H)-trione

DATABASE IDS

CAS Number 28882-53-3

PROPERTIES

Certificate of Analysis Download
Apperance Orange Solid
Melting Point 160-162°C
Solubility Chloroform
Solubility Ethyl Acetate
Solubility Methanol
MSDS Link Download
Storage Condition Amber Vial, -20°C Freezer

DETAILS

Description (English)
An angucycline antibiotic. A novel Stat3 selective inhibitor. It inhibits Stat3 dimerazation and DNA binding as well as Stat3-dependent luciferase reporter activity.

REFERENCES

  • Song, H., et al.: Natl. Acad. Sci. USA, 102, 4700 (2005)