NU 7441

• Catalog No.: N925300
• CAS Number: 503468-95-9
• M. F.: C25H19NO3S
• M. W.: 413.48826

SYNONYMS

• IUPAC name: 2-(morpholin-4-yl)-8-{8-thiatricyclo[7.4.0.0^2,^7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl}-4H-chromen-4-one
• IUPAC Traditional name: 2-(morpholin-4-yl)-8-{8-thiatricyclo[7.4.0.0^2,^7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl}chromen-4-one
• Synonyms: KU 57788; 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one

DATABASE IDS

• CAS Number: 503468-95-9

DETAILS

Description (English)

A potent novel DNA-dependent protein kinase inhibitor models of human cancer. Antitumor agent.

REFERENCES

• Caldecott, K., et al.: Cancer Res., 50, 5778 (1990)
• Boulton, S., et al.: Eur. J. Cancer, 36, 535 (1990)
• Jackson, S., et al.: Carcinogenesis, 23, 687 (1990)
• Sandler, A., et al.: Semin. Oncol., 30, 9 (1990)
• Hardcastle, I., et al.: J. Med. Chem., 48, 782