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Novobiocin Sodium Salt

Catalog No. N888500 Name Toronto Research Chemicals
CAS Number 1476-53-5 Website http://www.trc-canada.com
M. F. C31H35N2NaO11 Telephone +1 (416) 665-9696
M. W. 634.60617 Fax +1 (416) 665-4439
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Storage Chembase ID: 106179

SYNONYMS

IUPAC name
sodium 7-{[(2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy}-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxo-2H-chromen-4-olate
IUPAC Traditional name
sodium 7-{[(2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy}-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxochromen-4-olate
Synonyms
Cathomycin Sodium Lyovac
N-[7-[[3-O-(Aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-butenyl)benzamide monosodium salt
NSC 2382
Vulcamycin
Albamycin Sodium
Cathomycin Sodium

DATABASE IDS

CAS Number 1476-53-5

PROPERTIES

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DETAILS

Description (English)
Novobiocin is an antibiotic that acts as an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Studies show that Novobiocin is also an inhibitor of retrovirus RNA-dependent DNA-polymerase. Novobiocin is used in the production of positivel

REFERENCES

  • Cozarelli, N.R.: Science, 207, 953 (1980)
  • Sumiyoshi, Y. et al.: J. Gen. Virol., 64, 2329 (1980)
  • Lockshon, G. et al.: Nucleic Acids Res., 11, 2999 (1980)