24-Nor Ursodeoxycholic Acid

• Catalog No.: N865300
• CAS Number: 99697-24-2
• M. F.: C23H38O4
• M. W.: 378.54542

SYNONYMS

• IUPAC name: (3R)-3-[(1S,2S,5R,7S,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]butanoic acid
• IUPAC Traditional name: (3R)-3-[(1S,2S,5R,7S,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]butanoic acid
• Synonyms: Norursodeoxycholic Acid; (3α,5β,7β)-3,7-Dihydroxy-24-norcholan-23-oic Acid; 3α,7β-Dihydroxy-24-nor-5β-cholan-23-oic Acid

DATABASE IDS

• CAS Number: 99697-24-2

DETAILS

Description (English)

Ursodeoxycholic Acid (U850000) derivative. 24-norUrsodeoxycholic acid is superior to Ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.

REFERENCES

• Seedorf, U., et al.: J. Biol. Chem., 269, 21277 (1994)
• Stolowich, N., et al.: Biochemistry, 36, 1719 (1994)