Nortilidine Hydrochloride_Molecular_structure_CAS_34596-11-7)

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Nortilidine Hydrochloride
Catalog No.	N831000	Name	Toronto Research Chemicals
CAS Number	34596-11-7	Website	http://www.trc-canada.com
M. F.	C16H22ClNO2	Telephone	+1 (416) 665-9696
M. W.	295.80438	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	Refrigerator	Chembase ID: 175721

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SYNONYMS

IUPAC name

ethyl (1R,2R)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate hydrochloride

IUPAC Traditional name

ethyl (1R,2R)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate hydrochloride

Synonyms

trans-2-Methylamino-1-phenyl-3-cyclohexene-1-carboxylic Acid Ethyl Ester Hydrochloride

DATABASE IDS

CAS Number

34596-11-7

PROPERTIES

Certificate of Analysis	Download
Apperance	Off-White Solid
Melting Point	213-215°C
Solubility	Chloroform
Solubility	Methanol
Solubility	Water
MSDS Link	Download
Storage Condition	Refrigerator

DETAILS

Description (English)

The active metabolite of Tilidine. A receptor antagonist. Nortilidine easily penetrates the blood-brain barrier and activates the μ-opioid receptor. The enzymes involved in Tilidine metabolism are unknown.

REFERENCES

Boesch, D., et al.: Cancer Res., 51, 4226 (1991)
Austin, R., et al.: Drug Metab. Dispos., 30, 1497 (1991)
Hajda, J., et al.: J. Clin. Pharmacol., 42, 1257 (1991)
Thierry, C., et al.: Eur. J. Pharmacol., 506, 205 (1991)