4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid

• Catalog No.: N825910
• CAS Number: 1759-35-9
• M. F.: C18H28O4
• M. W.: 308.41252

SYNONYMS

• IUPAC name: 3-[(3S,3aS,5aS,6R,9aS,9bS)-3-hydroxy-3a,6-dimethyl-7-oxo-dodecahydro-1H-cyclopenta[a]naphthalen-6-yl]propanoic acid
• IUPAC Traditional name: 3-[(3S,3aS,5aS,6R,9aS,9bS)-3-hydroxy-3a,6-dimethyl-7-oxo-decahydrocyclopenta[a]naphthalen-6-yl]propanoic acid
• Synonyms: 3,5-Seco-A-norandrostan-17β-ol-5-on-3-oic Acid; [3S-(3α,3aα,5aβ,6β,9aα,9bβ)]-Dodecahydro-3-hydroxy-3a,6-dimethyl-7-oxo-1H-benz[e]indene-6-propanoic Acid; 17β-Hydroxy-5-oxo-A-nor-3,5-secoandrostan-3-oic Acid; (3S,3aS,5aS,6R,9aS,9bS)-Dodecahydro-3-hydroxy-3a,6-dimethyl-7-oxo-1H-benz[e]indene-6-propanoic Acid

DATABASE IDS

• CAS Number: 1759-35-9

DETAILS

Description (English)

4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid is an open A-ring steroid that showed inhibitory activity on hormone binding by an extract from Nippostrongylus brasiliensis (Nematoda). It is used in the preparation on heterocyclic steroids.

REFERENCES

• Majundar, T.K. et al.: Comp. Biochem. Physiol. Biochem. Mol. Biol., 88B, 81 (1987)
• Borthakur, M. et al.: Steroids, 73, 637 (1987)