18-Nor-17β-estradiol-d4

• Catalog No.: N674802
• M. F.: C17H22O2
• M. W.: 258.35538

SYNONYMS

• IUPAC name: (1S,10S,11S,14S,15S)-(13,13,14,15-^2H₄)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2(7),3,5-triene-5,14-diol
• IUPAC Traditional name: (1S,10S,11S,14S,15S)-(13,13,14,15-^2H₄)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2(7),3,5-triene-5,14-diol
• Synonyms: Gona-1,3,5(10)-triene-3,17β-diol-d4; (17β)-Gona-1,3,5(10)-triene-3,17-diol-d4; 17β,18-Norestradiol-d4; 18,19-Dinorandrosta-1,3,5(10)-triene-3,17β-diol-d4

DETAILS

Description (English)

A novel Estradiol (E888000) intermediate as selectively active estrogens. The specificity of the estrogen-receptor in human breast carcinoma was determine by incubating the cytosol fraction with 17β-estradiol-3H alone or in the presence of other steroids.

REFERENCES

• Loke, K., et al.: J. Biochem., 71, 230 (1957)