18-Nor-17β-estradiol

• Catalog No.: N674800
• CAS Number: 15093-14-8
• M. F.: C17H22O2
• M. W.: 258.35538

SYNONYMS

• IUPAC name: (1S,10S,11S,14S,15S)-tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2(7),3,5-triene-5,14-diol
• IUPAC Traditional name: (1S,10S,11S,14S,15S)-tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2(7),3,5-triene-5,14-diol
• Synonyms: 17β,18-Norestradiol; (17β)-Gona-1,3,5(10)-triene-3,17-diol; Gona-1,3,5(10)-triene-3,17β-diol; 18,19-Dinorandrosta-1,3,5(10)-triene-3,17β-diol

DATABASE IDS

• CAS Number: 15093-14-8

DETAILS

Description (English)

A novel Estradiol (E888000) intermediate as selectively active estrogens. The specificity of the estrogen-receptor in human breast carcinoma was determine by incubating the cytosol fraction with 17β-estradiol-3H alone or in the presence of other steroids.

REFERENCES

• Loke, K., et al.: J. Biochem., 71, 230 (1957)