Nordihydro Guaiaretic Acid (mixture of diastereomers)

• Catalog No.: N673000
• CAS Number: 500-38-9
• M. F.: C18H22O4
• M. W.: 302.36488
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-{3-[(3,4-dihydroxyphenyl)methyl]-2-methylbutyl}benzene-1,2-diol
• IUPAC Traditional name: nordihydroguaiaretic acid
• Synonyms: NDGA; NSC 4291; Nordihydroguaiaretic Acid; Dihydronorguaiaretic Acid; 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis-1,2-benzenediol; 4,4'-(2,3-Dimethyltetramethyl-ene)dipyrocatechol; β,γ-Dimethyl-α,δ-bis(3,4-dihydroxyphenyl)butane

DATABASE IDS

• CAS Number: 500-38-9

PROPERTIES

• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Apperance: Tan Solid
• Melting Point: 176-179°C (dec.)
• Solubility: DMSO
• Solubility: Methanol

DETAILS

Description (English)

Lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure. Inhibitor of broad bean lipoxygenase. The oxidation product from Resveratrol (R150000) showed a high inhibitory activity, whereas Resveratrol itself had no activity and its oxida

REFERENCES

• Brash, A., et al.: J. Biol. Chem., 274, 23679 (1999)
• Fujimoto, A., et al.: Bioorg. Med. Chem. Lett., 20, 7393 (1999)
• Ridolfi, M., et al.: J. Agric. Food Chem., 50, 835 (1999)