Nor-Desoxycholic Acid

• Catalog No.: N672000
• CAS Number: 53608-86-9
• M. F.: C23H38O4
• M. W.: 378.54542
• Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere

SYNONYMS

• IUPAC name: (3R)-3-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]butanoic acid
• IUPAC Traditional name: (3R)-3-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]butanoic acid
• Synonyms: 24-Nordeoxycholic Acid; 23-Nordeoxycholic Acid; Nordeoxycholic Acid; 3α,12α-Dihydroxy-24-nor-5β-cholan-23-oic Αcid; (3α,5β,12α)-3,12-Dihydroxy-24-norcholan-23-oic Acid

DATABASE IDS

• CAS Number: 53608-86-9

PROPERTIES

• Apperance: White Solid
• Melting Point: 185-188°C
• Solubility: Acetone
• Solubility: Dichloromethane
• Solubility: Ethanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Storage Warning: Hygroscopic

DETAILS

Description (English)

A derivative of Deoxycholic acid (DC); the bile acid nor-DC showed considerable and continuing efflux into the perfusate; this involved mostly the unchanged acid. Nor-DC was not amidated but was metabolized to mostly ester glucuronides and hydroxylated de

REFERENCES

• Haslewood, G., et al.: Biochem. J., 62, 637 (1956)
• Clayton, L. M., et al.: J. Pharmacol. Exp. Therap., 248, 1130 (1956)
• Aggarwal, S., et al.: Steroids, 57, 107 (1956)
• Batta, A., et al.: J. Lipid Res., 33, 1403 (1956)