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Norbuprenorphine

Catalog No. N661300 Name Toronto Research Chemicals
CAS Number 78715-23-8 Website http://www.trc-canada.com
M. F. C25H35NO4 Telephone +1 (416) 665-9696
M. W. 413.5497 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer, Under Inert Atmosphere Chembase ID: 175582

SYNONYMS

IUPAC name
(1S,2R,6S,14R,15R,16R)-16-(2-hydroxy-3,3-dimethylbutan-2-yl)-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-11-ol
IUPAC Traditional name
(1S,2R,6S,14R,15R,16R)-16-(2-hydroxy-3,3-dimethylbutan-2-yl)-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-11-ol
Synonyms
N-Dealkylbuprenorphine
N-De(cyclopropylmethyl)buprenorphine
N-Desalkylbuprenorphine
(αS,5α,7α)-α-(1,1-Dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol

DATABASE IDS

CAS Number 78715-23-8

PROPERTIES

Certificate of Analysis Download
Apperance Light Brown Solid
Melting Point 221-224°C
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
A metabolite of Buprenorphine.

REFERENCES

  • Cone, E., et al.: Drug Metab. Dispos., 12, 577 (1984)
  • Chauvin, M., et al.: Anesthesiology, 66, 327 (1984)
  • Ceccato, A., et al.: J. Pharm. Biomed. Anal., 32, 619 (1984)
  • Sittl, R., et al.: Clin. Ther., 27, 225 (1984)