R-(-)-Norapomorphine Hydrochloride

• Catalog No.: N661030
• CAS Number: 420382-69-8
• M. F.: C16H16ClNO2
• M. W.: 289.75674
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (9R)-10-azatetracyclo[7.7.1.0^2,^7.0^1^3,^1^7]heptadeca-1(17),2,4,6,13,15-hexaene-3,4-diol hydrochloride
• IUPAC Traditional name: (9R)-10-azatetracyclo[7.7.1.0^2,^7.0^1^3,^1^7]heptadeca-1(17),2,4,6,13,15-hexaene-3,4-diol hydrochloride
• Synonyms: (6aR)-5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol Hydrochloride; 6aβ-Noraporphine-10,11-diol Hydrochloride; Norapomorphin Hydrochloride; (-)-Norapomorphine Hydrochloride; Norapomorphine Hydrochloride

DATABASE IDS

• CAS Number: 420382-69-8

PROPERTIES

• Apperance: Green Solid
• Melting Point: >230°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

An Apomorphine derivative as inhibitor of amyloid-β (Aβ) fibril formation and their use in amyloidosis based disease.

REFERENCES

• Howlett, D., et al.: Biochem. J., 340, 283 (1999)
• Kuner, P., et al.: J. Biol. Chem., 275, 1673 (1999)
• Ono, K., et al.: J. Neurosci. Res., 75, 742 (1999)