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rac-N'-Nitroso Nornicotine _Molecular_structure_CAS_80508-23-2)
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rac-N'-Nitroso Nornicotine

Catalog No. N535000 Name Toronto Research Chemicals
CAS Number 80508-23-2 Website http://www.trc-canada.com
M. F. C9H11N3O Telephone +1 (416) 665-9696
M. W. 177.20314 Fax +1 (416) 665-4439
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Storage -20°C Freezer Chembase ID: 157162

SYNONYMS

IUPAC name
3-(1-nitrosopyrrolidin-2-yl)pyridine
IUPAC Traditional name
nitrosonornicotine
Synonyms
syn-N’-Nitrosonornicotine
3-(1-Nitroso-2-pyrrolidinyl)pyridine
3-[(2R,S)-1-Nitroso-2-pyrrolidinyl]pyridine
anti-N’-Nitrosonornicotine
NNN

DATABASE IDS

CAS Number 80508-23-2

PROPERTIES

Certificate of Analysis Download
Apperance Light Yellow Low Melting Solid
Solubility Acetone
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
N'-Nitrosonornicotine (NNN) is a tobacco alkaloid known as esophageal carcinogen. NNN is the cause of esophageal and oral cavity cancer in smokers and snuff dippers. The studies showed that the carcinogenicity of (S)-NNN, the predominant enantiomer in to

REFERENCES

  • Anto, R., et al.: Carcinogenesis, 23, 1511 (2002)
  • Pfeifer, G., et al.: Oncogene, 21, 7435 (2002)
  • Shishodia, S., et al.: Cancer Res., 64, 5004 (2002)
  • Jin, Z., et al.: J. Biol. Chem., 279, 23837 (2002)