rac-N'-Nitroso Nornicotine

• Catalog No.: N535000
• CAS Number: 80508-23-2
• M. F.: C9H11N3O
• M. W.: 177.20314
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 3-(1-nitrosopyrrolidin-2-yl)pyridine
• IUPAC Traditional name: nitrosonornicotine
• Synonyms: syn-N’-Nitrosonornicotine; 3-(1-Nitroso-2-pyrrolidinyl)pyridine; 3-[(2R,S)-1-Nitroso-2-pyrrolidinyl]pyridine; anti-N’-Nitrosonornicotine; NNN

DATABASE IDS

• CAS Number: 80508-23-2

PROPERTIES

• Apperance: Light Yellow Low Melting Solid
• Solubility: Acetone
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

N'-Nitrosonornicotine (NNN) is a tobacco alkaloid known as esophageal carcinogen. NNN is the cause of esophageal and oral cavity cancer in smokers and snuff dippers. The studies showed that the carcinogenicity of (S)-NNN, the predominant enantiomer in to

REFERENCES

• Anto, R., et al.: Carcinogenesis, 23, 1511 (2002)
• Pfeifer, G., et al.: Oncogene, 21, 7435 (2002)
• Shishodia, S., et al.: Cancer Res., 64, 5004 (2002)
• Jin, Z., et al.: J. Biol. Chem., 279, 23837 (2002)