Nitisinone-13C6

• Catalog No.: N490137
• CAS Number: 1246815-63-3
• M. F.: C14H10F3NO5
• M. W.: 335.18403863
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-[2-nitro-4-(trifluoromethyl)benzoyl](1,2,3,4,5,6-^1^3C₆)cyclohexane-1,3-dione
• IUPAC Traditional name: 2-[2-nitro-4-(trifluoromethyl)benzoyl](1,2,3,4,5,6-^1^3C₆)cyclohexane-1,3-dione
• Synonyms: NTBC-13C6; SC 0735-13C6; 2-[2-Nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione-13C6; Orfadin-13C6; Nitisone-13C6

DATABASE IDS

• CAS Number: 1246815-63-3

PROPERTIES

• Apperance: Tan Solid
• Melting Point: 132-134°C
• Solubility: Chloroform
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled Nitisinone. Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyro

REFERENCES

• Lindstedt, S., et al.: Lancet, 340, 813 (1992)
• Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1992)
• Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1992)