β-Nicotinamide Mononucleotide-13C5

• Catalog No.: N407767
• M. F.: C11H15N2O8P
• M. W.: 339.18243519

SYNONYMS

• IUPAC name: 3-carbamoyl-1-[(2R,4S,5R)-5-[(hydrogen phosphonatooxy)(^1^3C)methyl]-3,4-dihydroxy(2,3,4,5-^1^3C₄)oxolan-2-yl]-1λ^5-pyridin-1-ylium
• IUPAC Traditional name: 3-carbamoyl-1-[(2R,4S,5R)-5-[(hydrogen phosphonatooxy)(^1^3C)methyl]-3,4-dihydroxy(2,3,4,5-^1^3C₄)oxolan-2-yl]-1λ^5-pyridin-1-ylium
• Synonyms: 3-Carbamoyl-1-β-D-ribofuranosylpyridinium Hydroxide 5'-Phosphate-13C5 Inner Salt; 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium-13C5 Inner Salt; β-D-NMN-13C5; Nicotinamide Ribonucleoside 5'-Phosphate-13C5; β-NMN-13C5; NMN-13C5; Nicotinamide Mononucleotide-13C5; Nicotinamide Ribonucleotide-13C5; Nicotinamide Ribotide-13C5

DETAILS

Description (English)

The labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic ins

REFERENCES

• Yoshino, J. et al.: Cell Metab., 14, 528 (2011)
• Caton, P.W. et al.: Diabetologia, 54, 3083 (2011)
• Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2011)