β-Nicotinamide Mononucleotide

• Catalog No.: N407765
• CAS Number: 1094-61-7
• M. F.: C11H15N2O8P
• M. W.: 334.219161

SYNONYMS

• IUPAC name: 3-carbamoyl-1-[(2R,4R,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1λ^5-pyridin-1-ylium
• IUPAC Traditional name: 3-carbamoyl-1-[(2R,4R,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1λ^5-pyridin-1-ylium
• Synonyms: NMN; Nicotinamide Ribotide; Nicotinamide Mononucleotide; β-D-NMN; Nicotinamide Ribonucleoside 5'-Phosphate; 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium Inner Salt; 3-Carbamoyl-1-β-D-ribofuranosylpyridinium Hydroxide, 5'-Phosphate Inner Salt; Nicotinamide Ribonucleotide; β-NMN

DATABASE IDS

• CAS Number: 1094-61-7

DETAILS

Description (English)

A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and rest

REFERENCES

• Yoshino, J. et al.: Cell Metab., 14, 528 (2011)
• Caton, P.W. et al.: Diabetologia, 54, 3083 (2011)
• Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2011)