Nevirapine-d3

• Catalog No.: N391278
• CAS Number: 1051419-24-9
• M. F.: C15H14N4O
• M. W.: 266.29786
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-cyclopropyl-7-(^2H₃)methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
• IUPAC Traditional name: 2-cyclopropyl-7-(^2H₃)methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
• Synonyms: 11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2’,3’-e][1,4]diazepin-6-one-d3; Nevarapine-d3; NSC 641530-d3; Viramune-d3; BI-RG 587-d3

DATABASE IDS

• CAS Number: 1051419-24-9

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 234-236°C
• Solubility: Chloroform
• Solubility: DMSO
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled Nevirapine (N391275), a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral.

REFERENCES

• Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991)
• Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1991)
• Guay, L.A., et al.: Lancet, 354, 795 (1991)