(-)-Nebivolol-d4 Hydrochloride

• Catalog No.: N387897
• M. F.: C22H26ClF2NO4
• M. W.: 441.8959464
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1S)-1-[(2S)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-{[(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxy(1,1-^2H₂)ethyl]amino}(2,2-^2H₂)ethan-1-ol hydrochloride
• IUPAC Traditional name: (1S)-1-[(2S)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-{[(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxy(1,1-^2H₂)ethyl]amino}(2,2-^2H₂)ethanol hydrochloride
• Synonyms: (αS,α’S,2R,2’S)-α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]-d4 Hydrochloride; [2S-[2R*[R*[R*(S*)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol-d4 Hydrochloride; l-Nebivolol-d4 Hydrochloride; Levonebivolol-d4 Hydrochloride; R-67145-d4 Hydrochloride

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 198-200°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled (-)-Nebivolol (N387895). A β1-Adrenergic blocker. Used as an antihypertensive.

REFERENCES

• Van de Water, A., et al.: J. Cardiovasc. Pharmacol., 11, 552 (1988)
• De Cree, J., et al.: Angiology, 41, 95 (1990)