(-)-Nebivolol

• Catalog No.: N387895
• CAS Number: 118457-16-2
• M. F.: C22H25F2NO4
• M. W.: 405.4350064
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S)-1-[(2R)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-{[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino}ethan-1-ol
• IUPAC Traditional name: l-nebivolol
• Synonyms: (αS,α’S,2R,2’S)-α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; [2S-[2R*[R*[R*(S*)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol; l-Nebivolol; R-67145; Levonebivolol

DATABASE IDS

• CAS Number: 118457-16-2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 135-137°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A β1-Adrenergic blocker. Used as an antihypertensive.

REFERENCES

• Van de Water, A., et al.: J. Cardiovasc. Pharmacol., 11, 552 (1988)
• De Cree, J., et al.: Angiology, 41, 95 (1990)