Naxagolide Hydrochloride

• Catalog No.: N379800
• CAS Number: 99705-65-4
• M. F.: C15H22ClNO2
• M. W.: 283.79368
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (4aR,10bR)-4-propyl-2H,3H,4H,4aH,5H,6H,10bH-naphtho[1,2-b]morpholin-9-ol hydrochloride
• IUPAC Traditional name: (4aR,10bR)-4-propyl-2H,3H,4aH,5H,6H,10bH-naphtho[1,2-b]morpholin-9-ol hydrochloride
• Synonyms: (4aR-trans)-3,4,4a,5,6,10b-Hexahydro-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-9-ol Hydrochloride; L 647339; (+)-Propyl-9-hydroxynaphthoxazine Hydrochloride; MK 458; (+)-PHNO Hydrochloride; Dopazinol Hydrochloride; Nazagolide HCl

DATABASE IDS

• CAS Number: 99705-65-4

PROPERTIES

• Apperance: Off-White to Tan Solid
• Melting Point: 296-298°C
• Solubility: Ethanol
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Refrigerator

DETAILS

Description (English)

A dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug.

REFERENCES

• Fujita, N., et al.: Brain Res., 333, 231 (1985)
• Weiss, F., et al.: Eur. J, Pharmacol., 337, 219 (1985)
• Wilson, A., et al.: J. Med. Chem., 48, 4153 (1985)
• Ginovart, N., et al.: J. Neurochem., 97, 1089 (1985)
• Willeit, M., et al.: Biol. Psychiatry, 59, 3