Nateglinide Acyl-β-D-glucuronide

• Catalog No.: N379380
• CAS Number: 183996-85-2
• M. F.: C25H35NO9
• M. W.: 493.5467
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{[(2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoyl]oxy}oxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{[(2R)-3-phenyl-2-{[(1r,4r)-4-isopropylcyclohexyl]formamido}propanoyl]oxy}oxane-2-carboxylic acid
• Synonyms: Nateglinide Acyl Glucuronide; N-[[trans-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine β-D-Glucopyranuronic Acid

DATABASE IDS

• CAS Number: 183996-85-2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 105-107°C
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Nateglinide (N379375), a novel D-phenylalanine-derivative hypoglycemic agent

REFERENCES

• Korzekwa, K., et al.: Drug Metab. Dispos., 18, 974 (1990)
• Takesada, H., et al.: Bioorg. Med. Chem., 4, 1771 (1990)
• Ikenoue, T., et al.: Br. J. Pharmacol., 120, 137 (1990)
• Karara, A., et al.: J. Clin. Pharmacol., 39, 172 (1990)
• Hanefeld, M., et al.: Di