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Naringin Hydrate

Catalog No. N378980 Name Toronto Research Chemicals
CAS Number 132203-74-8 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
(2S)-7-{[(2S,4S,5S)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(3R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
IUPAC Traditional name
(2S)-7-{[(2S,4S,5S)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(3R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzopyran-4-one
Synonyms
Naringenin 7-Neohesperidoside Hydrate
Aurantiin Hydrate
(S)-7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Hydrate

DATABASE IDS

CAS Number 132203-74-8

PROPERTIES

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DETAILS

Description (English)
The major flavonoid found in grapefruit juice. It has antioxidant, lipid lowering, and anticancer activities. It is also an inhibitor of cytochrome P450 enzymes, affecting drug metabolism and thus drug absorption in humans.

REFERENCES

  • Su, Z., et al.: J. Pharm. Biomed. Anal., 53, 454 (2010)
  • Carino-Cortes, R., et al.: Biol. Pharm. Bull., 33, 697 (2010)
  • Jordan, M., et al.: J. Agric. Food Chem., 58, 8265 (2010)