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Nilotinib-d3
Catalog No.	N465302	Name	Toronto Research Chemicals
CAS Number		Website	http://www.trc-canada.com
M. F.	C28H22F3N7O	Telephone	+1 (416) 665-9696
M. W.	529.5157896	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	-20°C Freezer	Chembase ID: 175011

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SYNONYMS

IUPAC name

4-methyl-N-{3-[4-(²H₃)methyl-1H-imidazol-1-yl]-5-(trifluoromethyl)phenyl}-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide

IUPAC Traditional name

4-methyl-N-{3-[4-(²H₃)methylimidazol-1-yl]-5-(trifluoromethyl)phenyl}-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide

Synonyms

Tasigna-d3

AMN 107-d3

4-Methyl-N-[3-(4-(methyl-d3)-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide

DATABASE IDS

PROPERTIES

Certificate of Analysis	Download
Apperance	Off-White to Pale Yellow Solid
Melting Point	227-230°C
Solubility	DMSO
MSDS Link	Download
Storage Condition	-20°C Freezer

DETAILS

Description (English)

Labelled analog of Nilotinib (AMN1O7), which might be useful in treatment of chronic myelogenous leukemia.

REFERENCES

Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002)
Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2002)
Gleixner, K., et al.: Blood, 107, 752 (2002)
Nicolini, F., et al.: Leukemia, 20, 1061 (2002)