(R)-Naproxen Acyl-β-D-glucuronide Benzyl Ester

• Catalog No.: N377518
• M. F.: C27H28O9
• M. W.: 496.50582

SYNONYMS

• IUPAC name: benzyl (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{[(2R)-2-(6-methoxynaphthalen-2-yl)propanoyl]oxy}oxane-2-carboxylate
• IUPAC Traditional name: benzyl (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{[(2R)-2-(6-methoxynaphthalen-2-yl)propanoyl]oxy}oxane-2-carboxylate
• Synonyms: 1-[(αR)-6-Methoxy-α-methyl-2-naphthaleneacetate] β-D-Glucopyranuronic Acid Benzyl Ester; (R)-Naproxen Glucuronide Benzyl Ester

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >180°C (dec.)
• Solubility: DMSO
• Solubility: Methanol

DETAILS

Description (English)

(R)-Naproxen Acyl-β-D-glucuronide benzyl ester is an acyl glucuronide metabolite derivative of (R)-Naproxen (N377510).

REFERENCES

• Spahn-Langguth, H., et al.: Drug Metab. Rev., 24, 5 (1992)
• Ebner, T., et al.: Drug Metab. Dispos., 27, 1143 (1992)
• Kenny, J., et al.: J. Med. Chem., 47, 2816 (1992)
• Vanderhoeven, S., et al.: Xenobiotica, 34, 889 (1992)