Naltrexone 3-Methyl Ether

• Catalog No.: N285765
• CAS Number: 16617-07-5
• M. F.: C21H25NO4
• M. W.: 355.4275

SYNONYMS

• IUPAC name: (1S,5R,13R,17S)-4-(cyclopropylmethyl)-17-hydroxy-10-methoxy-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-14-one
• IUPAC Traditional name: (1S,5R,13R,17S)-4-(cyclopropylmethyl)-17-hydroxy-10-methoxy-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-14-one
• Synonyms: 17-(Cyclopropylmethyl)-4,5α-epoxy-14-hydroxy-3-methoxy-morphinan-6-one; N-Cyclopropylmethylnoroxycodone; Naltrexone-3-methyl Ether; 3-Methoxynaltrexone; O3-Methyl-(-)-naltrexone; 3-O-Methylnaltrexone

DATABASE IDS

• CAS Number: 16617-07-5

PROPERTIES

• Apperance: Off-White Solid
• Solubility: DMSO
• Solubility: Methanol

DETAILS

Description (English)

A potent antagonist of the antinociceptive effects of heroin.

REFERENCES

• Teppema, L., et al.: Anesthesiol., 109, 689 (2008)
• Cami-Kobeci, G., et al.: J. Med. Chem., 52, 1546 (2008)
• Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 121 (2008)