Naltrexone 3-O-β-D-Glucuronide

• Catalog No.: N285760
• CAS Number: 76630-71-2
• M. F.: C26H31NO10
• M. W.: 517.52504
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-{[(1S,5R,13R,17S)-4-(cyclopropylmethyl)-17-hydroxy-14-oxo-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-10-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-{[(1S,5R,13R,17S)-4-(cyclopropylmethyl)-17-hydroxy-14-oxo-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-10-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-14-hydroxy-6-oxomorphinan-3-yl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 76630-71-2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >132°C (dec.)
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Naltrexone. Narcotic antagonist. Used in treatment of alcoholism.

REFERENCES

• Rodgers, R.M., et al.: Drug Metab. Dispos., 8, 390 (1980)
• Yaksh, T., et al.: J. Pharmacol. Exp. Ther., 244, 501 (1980)