Naloxone Hydrochloride

• Catalog No.: N285000
• CAS Number: 357-08-4
• M. F.: C19H22ClNO4
• M. W.: 363.83528
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-14-one hydrochloride
• IUPAC Traditional name: naloxone hydrochloride
• Synonyms: Narcan; EN-15304; Narcanti; (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one Hydrochloride; 17-Allyl-4,5α-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride; Nalone

DATABASE IDS

• CAS Number: 357-08-4

PROPERTIES

• Apperance: White Solid
• Melting Point: 202-205°C
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Specific opioid antagonist. Narcotic antagonist.

REFERENCES

• Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967)
• McNicholas, L.F., et al.: Drugs, 27, 81 (1967)
• Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1967)
• Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1967)