Naloxol 3-β-D-Glucuronide

• Catalog No.: N284510
• CAS Number: 24326-39-4
• M. F.: C25H31NO10
• M. W.: 505.51434

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-{[(1S,5R,13R,17S)-14,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-10-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-{[(1S,5R,13R,17S)-14,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-10-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: Naloxol-3-glucuronide; (5α)-4,5-Epoxy-6,14-dihydroxy-17-(2-propenyl)morphinan-3-yl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 24326-39-4

DETAILS

Description (English)

A metabolite of Naloxone (N285000). Narcotic antagonist.

REFERENCES

• Scheurer, U., et al.: J. Pharmacol. Exp. Ther., 252, 1324 (1990)
• Yuan, C., et al.: Clin. Pharmacol. Ther., 59, 469 (1990)
• Ulens, C., et al.: Biochem. Pharmacol., 62, 1273 (1990)
• Comert, M., et al.: Eur. J. Pharmacol., 511, 183 (1990)