6α-Naloxol Hydrochloride

• Catalog No.: N284500
• CAS Number: 34520-00-8
• M. F.: C19H24ClNO4
• M. W.: 365.85116

SYNONYMS

• IUPAC name: (1S,5R,13R,14S,17S)-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,14,17-triol hydrochloride
• IUPAC Traditional name: naloxol hydrochloride
• Synonyms: N-Allyl-7,8-dihydro-14-hydroxynormorphine Hydrochloride; (5α,6α)-4,5-Εpoxy-17-(2-propen-1-yl)-morphinan-3,6,14-triol Hydrochloride; 6-Hydroxynaloxone Hydrochloride; α-Naloxol Hydrochloride; EN 2265A; N-Allyl-14-hydroxy-7,8-dihydronormorphine Hydrochloride

DATABASE IDS

• CAS Number: 34520-00-8

DETAILS

Description (English)

A metabolite of Naloxone (N285000). Naltrexone analog and Naloxone analog neutral μ-opioid antagonists and use thereof in treating drug abuse and pain.

REFERENCES

• Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975)
• Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1975)
• Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (1975)