Nalmefene-d3

• Catalog No.: N284402
• M. F.: C21H25NO3
• M. W.: 339.4281

SYNONYMS

• IUPAC name: (1S,5R,13S,17S)-4-[(1-^2H)cyclopropyl(^2H₂)methyl]-14-methylidene-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,17-diol
• IUPAC Traditional name: (1S,5R,13S,17S)-4-[(1-^2H)cyclopropyl(^2H₂)methyl]-14-methylidene-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,17-diol
• Synonyms: 6-Deoxo-6-methylenenaltrexone-d3; (5α)-17-(Cyclopropylmethyl-d3)-4,5-epoxy-6-methylenemorphinan-3,14-diol; 6-Desoxy-6-methylenenaltrexone-d3; ORF 11676-d3; (-)-Nalmefene-d3; JF 1-d3; Nalmetrene-d3

DETAILS

Description (English)

A structural labelled analog of Naltrexone (N285780) with opiate antagonist activity used in pharmaceutical treatment of alcoholism. Other pharmacological applications of this compound aim to reduce food cravings, drug abuse and pulmonary disease in affec

REFERENCES

• Brittain, H.G., et al.: Anal. Profiles Drug Subs. Excip., 24, 351 (1996)
• Anton, R., et al.: J. Clin. Psychopharmacol., 24, 421 (1996)
• Bart, G., et al.: Neuropsychopharmacol., 30, 2254 (1996)
• Wu, X., et al.: Chem. Pharmacol. Bull., 54, 977 (1996)