Myriocin

• Catalog No.: M884400
• CAS Number: 35891-70-4
• M. F.: C21H39NO6
• M. W.: 401.53746

SYNONYMS

• IUPAC name: (3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
• IUPAC Traditional name: (3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
• Synonyms: (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid; (+)-Myriocin; Thermozymocidin; [2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; NSC 177379; (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic Acid; ISP-I

DATABASE IDS

• CAS Number: 35891-70-4

DETAILS

Description (English)

Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine pal

REFERENCES

• Miyake, Y., et al.: Biochem. Biophys. Res. Commun., 211, 396 (1995)
• Hidari, K.I.P.J. et al.: J. Biol. Chem., 271, 14636 (1995)
• Nakamura, S. et al.: J. Biol. Chem., 271, 1255 (1995)
• De Zélicourt, A. et al.: Planta 230, 1047 (1995)