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Myriocin

Catalog No. M884400 Name Toronto Research Chemicals
CAS Number 35891-70-4 Website http://www.trc-canada.com
M. F. C21H39NO6 Telephone +1 (416) 665-9696
M. W. 401.53746 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 134017

SYNONYMS

IUPAC name
(3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
IUPAC Traditional name
(3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
Synonyms
(2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid
(+)-Myriocin
Thermozymocidin
[2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid
NSC 177379
(2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic Acid
ISP-I

DATABASE IDS

CAS Number 35891-70-4

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine pal

REFERENCES

  • Miyake, Y., et al.: Biochem. Biophys. Res. Commun., 211, 396 (1995)
  • Hidari, K.I.P.J. et al.: J. Biol. Chem., 271, 14636 (1995)
  • Nakamura, S. et al.: J. Biol. Chem., 271, 1255 (1995)
  • De Zélicourt, A. et al.: Planta 230, 1047 (1995)