Mycophenolic Acid Methyl Ester 6-Methyl β-D-Glucuronate

• Catalog No.: M831540
• M. F.: C25H32O12
• M. W.: 524.51438

SYNONYMS

• IUPAC name: methyl (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-({6-methoxy-5-[(2E)-6-methoxy-3-methyl-6-oxohex-2-en-1-yl]-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-4-yl}oxy)oxane-2-carboxylate
• IUPAC Traditional name: methyl (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-({6-methoxy-5-[(2E)-6-methoxy-3-methyl-6-oxohex-2-en-1-yl]-7-methyl-3-oxo-1H-2-benzofuran-4-yl}oxy)oxane-2-carboxylate
• Synonyms: Methyl Mycophenolic Acid Methyl Ester Glucosiduronate

DETAILS

Description (English)

A labelled metabolite of Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in t

REFERENCES

• Senda, M., et al.: Transplantation, 60, 1143 (1995)
• Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1995)
• Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1995)