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(S)-M8-SPy

Catalog No. M755300 Name Toronto Research Chemicals
CAS Number 1192364-56-9 Website http://www.trc-canada.com
M. F. C31H52N6O7S2 Telephone +1 (416) 665-9696
M. W. 684.91058 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 174848

SYNONYMS

IUPAC name
(2S)-2-[(2S,5S,8S,11S)-4,10-bis[(1S)-1-carboxyethyl]-2,5,8,11-tetramethyl-7-[(1S)-1-{[2-(pyridin-2-yldisulfanyl)ethyl]carbamoyl}ethyl]-1,4,7,10-tetraazacyclododecan-1-yl]propanoic acid
IUPAC Traditional name
(2S)-2-[(2S,5S,8S,11S)-4,10-bis[(1S)-1-carboxyethyl]-2,5,8,11-tetramethyl-7-[(1S)-1-{[2-(pyridin-2-yldisulfanyl)ethyl]carbamoyl}ethyl]-1,4,7,10-tetraazacyclododecan-1-yl]propanoic acid
Synonyms
(α1S,α4S,α7S,2S,5S,8S,11S)-α1,α4,α7,2,5,8,11-Heptamethyl-10-[(1S)-1-methyl-2-oxo-2-[[2-(2-pyridinyldithio)ethyl]amino]ethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic Acid

DATABASE IDS

CAS Number 1192364-56-9

PROPERTIES

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DETAILS

Description (English)
A new lanthanide chelating tag (M8) for paramagnetic labeling of biomols. is presented, which is based on an eight-fold, stereoselectively methyl-substituted DOTA that can be covalently linked to the host molecule by a single disulfide bond. The steric ov

REFERENCES

  • Ebright, Y., et al.: Biochemistry, 31, 10664 (1992)
  • Gaponenko, V., et al.: Biochemistry, 2000, 39, 15217 (1992)
  • Su, X., et al.: ChemBioChem., 7, 1599 (1992)