Montelukast 1,2-Diol(Mixture of Diastereomers)

• Catalog No.: M568015
• CAS Number: 186352-97-6
• M. F.: C35H36ClNO4S
• M. W.: 602.18264
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-[1-({[(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(1,2-dihydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid
• IUPAC Traditional name: [1-({[(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(1,2-dihydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid
• Synonyms: 1-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1,2-diol-2-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic; M6a,b

DATABASE IDS

• CAS Number: 186352-97-6

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 78-80°C
• Solubility: Acetone
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

The methyl-hydroxylated metabolite of Montelukast.

REFERENCES

• Madan, A., et al.: Biochem. Pharmacol., 46, 2291 (1993)
• Blake, B.L., et al.: Xenobiotica, 25, 377 (1993)
• LaBelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1993)
• Chiba, M., et al.: Drug Metab. Dispos., 24, 307 (1993)