ent-Montelukast Sodium Salt

• Catalog No.: M567995
• CAS Number: 190078-45-6
• M. F.: C35H35ClNNaO3S
• M. W.: 608.16507
• Storage: Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: sodium 2-[1-({[(1S)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetate
• IUPAC Traditional name: sodium 2-[1-({[(1S)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetate
• Synonyms: 1-[[[(1S)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic Acid Sodium Salt; L 768232

DATABASE IDS

• CAS Number: 190078-45-6

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 112-115°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

The S-enantiomer of Montelukast. Results indicate that there is no apparent bioinversion of Montelukast to its S-enantiomer in humans.

REFERENCES

• Cheng, H., et al.: Pharm. Res., 11, 824 (1994)
• Amin, R., et al.: J. Pharm. Biomed. Anal., 13, 155 (1994)
• Jones, T., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1994)
• Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1994)