Motexafin Lutetium Hydrate

• Catalog No.: M732700
• CAS Number: 156436-90-7
• M. F.: C52H74LuN5O15
• M. W.: 1184.13526

SYNONYMS

• IUPAC name: (acetyloxy)[4,5-diethyl-9,24-bis(3-hydroxypropyl)-16,17-bis({2-[2-(2-methoxyethoxy)ethoxy]ethoxy})-10,23-dimethyl-13,20,25,26,27-pentaazapentacyclo[20.2.1.1^3,^6.1^8,^1^1.0^1^4,^1^9]heptacosa-1,3,5,7,9,11(26),12,14,16,18,20,22(25),23-tridecaen-27-yl]lutetio acetate hydrate
• IUPAC Traditional name: (acetyloxy)[4,5-diethyl-9,24-bis(3-hydroxypropyl)-16,17-bis({2-[2-(2-methoxyethoxy)ethoxy]ethoxy})-10,23-dimethyl-13,20,25,26,27-pentaazapentacyclo[20.2.1.1^3,^6.1^8,^1^1.0^1^4,^1^9]heptacosa-1,3,5,7,9,11(26),12,14,16,18,20,22(25),23-tridecaen-27-yl]lutetio acetate hydrate
• Synonyms: (PB-7-11-233'2'4)-Bis(acetato-κO)[9,10-diethyl-20,21-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-4,15-dimethyl-8,11-imino-3,6:16,13-dinitrilo-1,18-benzodiazacycloeicosine-5,14-dipropanolato-κN1,κN18,κN23,κN24,κN25]lutetium Hydrate; NSC 695239; PCI 0123

DATABASE IDS

• CAS Number: 156436-90-7

DETAILS

Description (English)

Synthetic metal-coordinating expanded porphyrin. Diamagnetic photosensitizer that is activated using far-red light to generate cytotoxic singlet oxygen. Antiatherosclerotic, antineoplastic (photosensitizer). Used in treatment of age-related macular degene

REFERENCES

• Young, S.W., et al.: Photochem. Photobiol., 63, 892 (1996)
• Kereiakes, D.J., et al.: Circulation, 108, 1310 (1996)