Moexiprilat-d5

• Catalog No.: M485362
• M. F.: C25H30N2O7
• M. W.: 470.5149

SYNONYMS

• IUPAC name: (3R)-2-[(2S)-2-{[(1S)-1-carboxy-3-(^2H₅)phenylpropyl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
• IUPAC Traditional name: (3R)-2-[(2S)-2-{[(1S)-1-carboxy-3-(^2H₅)phenylpropyl]amino}propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
• Synonyms: RS 10029; [3S-[2[R*(R*)],3R*]]-2-[2-[(1-Carboxy-3-(phenyl-d5)propyl)amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid; (3S)-2-[(2S)-2-[[(1S)-1-Carboxy-3-(phenyl-d5)propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid

PROPERTIES

• Apperance: White Crystalline Solid
• Melting Point: 145-170°C
• Solubility: Methanol
• Solubility: Tetrahydrofuran

DETAILS

Description (English)

Labelled Moexiprilat (M485360). Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of Quinapril. Antihypertensive.

REFERENCES

• Klutchko, et al.: J. Med. Chem., 29, 1953 (1986)
• Edling, O., et al.: J. Pharmacol. Exp. Ther., 275, 854 (1986)
• Stimpel, M., et al.: Cardiology, 87, 313 (1986)