MLN 8054

• Catalog No.: M425125
• CAS Number: 869363-13-3
• M. F.: C25H15ClF2N4O2
• M. W.: 476.8620064

SYNONYMS

• IUPAC name: 4-{[13-chloro-10-(2,6-difluorophenyl)-3,5,9-triazatricyclo[9.4.0.0^2,^7]pentadeca-1(11),2(7),3,5,9,12,14-heptaen-4-yl]amino}benzoic acid
• IUPAC Traditional name: 4-{[13-chloro-10-(2,6-difluorophenyl)-3,5,9-triazatricyclo[9.4.0.0^2,^7]pentadeca-1(11),2(7),3,5,9,12,14-heptaen-4-yl]amino}benzoic acid
• Synonyms: 4-[[9-Chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic Acid

DATABASE IDS

• CAS Number: 869363-13-3

DETAILS

Description (English)

An Aurora kinase inhibitor, used to treat patients with advanced solid tumors.

REFERENCES

• Kaestner, P., et al.: Mol. Cancer Ther., 8, 2046 (2009)
• Scutt, P., et al.: J. Biol. Chem., 284, 15880 (2009)
• Aliagas-Martin, I., et al.: J. Med. Chem., 52, 3300 (2009)