Micafungin Sodium

• Catalog No.: M342350
• CAS Number: 208538-73-2
• M. F.: C56H71N9O23S
• M. W.: 1270.27444

SYNONYMS

• IUPAC name: {5-[(1S,2S)-2-[(3S,6S,9S,11R,18S,20R,21R,24S,25S,26S)-3-[(1R)-2-carbamoyl-1-hydroxyethyl]-11,20,21,25-tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-(4-{5-[4-(pentyloxy)phenyl]-1,2-oxazol-3-yl}benzamido)-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0^9,^1^3]heptacosan-6-yl]-1,2-dihydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid
• IUPAC Traditional name: {5-[(1S,2S)-2-[(3S,6S,9S,11R,18S,20R,21R,24S,25S,26S)-3-[(1R)-2-carbamoyl-1-hydroxyethyl]-11,20,21,25-tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-(4-{5-[4-(pentyloxy)phenyl]-1,2-oxazol-3-yl}benzamido)-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0^9,^1^3]heptacosan-6-yl]-1,2-dihydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid
• Synonyms: FK 463; Funguard; 1-[(4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0 Monosodium Salt

DATABASE IDS

• CAS Number: 208538-73-2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >211°C (dec.)
• Solubility: DMSO
• Solubility: Water

DETAILS

Description (English)

An echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.

REFERENCES

• Chen, S.C. et al.: Drugs, 71, 11 (2011)
• Groll, A.H. et al.: Opin. Anti-Infect. Invest. Drugs, 2, 405 (2011)
• Tomishima, M. et al.: J. Antibiot., 52, 674 (2011)