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2'-O-Methyl Uridine_Molecular_structure_CAS_2140-76-3)
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2'-O-Methyl Uridine

Catalog No. M338200 Name Toronto Research Chemicals
CAS Number 2140-76-3 Website http://www.trc-canada.com
M. F. C10H14N2O6 Telephone +1 (416) 665-9696
M. W. 258.22796 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 153577

SYNONYMS

IUPAC name
1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC Traditional name
1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-pyrimidine-2,4-dione
Synonyms
O2'-Methyluridine

DATABASE IDS

CAS Number 2140-76-3

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 154-156°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.

REFERENCES

  • Gratzner, H., et al.: Science, 218, 474 (1982)
  • Jarvis, T., et al.: J. Biol. Chem., 271, 29107 (1982)
  • Pavco, P., et al.: Clin. Cancer Res., 6, 2094 (1982)