4-Methylumbelliferyl α-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt

• Catalog No.: M334715
• M. F.: C16H14Na2O12S
• M. W.: 476.3197
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: disodium (2R,3S,4S,5R,6S)-3,4-dihydroxy-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]-5-(sulfonatooxy)oxane-2-carboxylate
• IUPAC Traditional name: disodium (2R,3S,4S,5R,6S)-3,4-dihydroxy-6-[(4-methyl-2-oxochromen-7-yl)oxy]-5-(sulfonatooxy)oxane-2-carboxylate
• Synonyms: 4-Methyl-2-oxo-2H-1-benzopyran-7-yl α-L-Idopyranosiduronic Acid 2-(Hydrogen Sulfate); 4-Methylumbelliferyl α-L-Iduronic Acid-2-sulfate Sodium Salt

PROPERTIES

• Apperance: White Solid
• Melting Point: >220°C (dec.)
• Solubility: Ethanol
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A fluorogenic substrate in the assay of α-L-Iduronidase. A fluorimetric enzyme assay for the diagnosis of MPS II (Hunter disease).

REFERENCES

• Matalon, R., et al.: Biochem. Biophys. Res. Commun., 47, 959 (1972)
• Voznyi, Y.V., et al.: J. Inherit. Metab. Dis., 24, 675 (2001)