MLN 8054 O-β-D-Glucuronide

• Catalog No.: M425130
• CAS Number: 1203589-02-9
• M. F.: C31H23ClF2N4O8
• M. W.: 652.9861264

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-(4-{[13-chloro-10-(2,6-difluorophenyl)-3,5,9-triazatricyclo[9.4.0.0^2,^7]pentadeca-1(11),2(7),3,5,9,12,14-heptaen-4-yl]amino}benzoyloxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-(4-{[13-chloro-10-(2,6-difluorophenyl)-3,5,9-triazatricyclo[9.4.0.0^2,^7]pentadeca-1(11),2(7),3,5,9,12,14-heptaen-4-yl]amino}benzoyloxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: 1-[4-[[9-Chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoate] β-D-Glucopyranuronic Acid

DATABASE IDS

• CAS Number: 1203589-02-9

DETAILS

Description (English)

A metabolite of MLN 8054 (M425125).

REFERENCES

• Aliagas-Martin, I., et al.: J. Med. Chem., 52, 3300 (2009)
• Kaestner, P., et al.: Mol. Cancer Ther., 8, 2046 (2009)
• Scutt, P., et al.: J. Biol. Chem., 284, 15880 (2009)