5-(Methyl-d3)tetrahydrofolic Acid (Mixture of Diastereomers)

• Catalog No.: M330137
• CAS Number: 1356019-97-0
• M. F.: C20H25N7O6
• M. W.: 459.4558
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S)-2-{[4-({[2-amino-5-(^2H₃)methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
• IUPAC Traditional name: (2S)-2-{[4-({[2-amino-5-(^2H₃)methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
• Synonyms: N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-5-(methyl-d3)-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; Prefolic A-d3; N-(Methyl-d3)tetrahydrofolate; N5-(Methyl-d3)tetrahydropteroylglutamate; N5-(Methyl-d3)tetrahydrofolate

DATABASE IDS

• CAS Number: 1356019-97-0

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: >200°C (dec.)
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A labelled metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA; reduces total serum homocysteine level in orthotopic liver transplant recipients.

REFERENCES

• Fassbender, K., et al.: Lancet, 353, 1586 (1999)
• Pruthi, J., et al.: Liver Transpl., 7, 811 (1999)
• Wu, L., et al.: Clin. Chim. Acta, 322, 21 (1999)
• Eisen, H., et al.: N. Engl. J. Med., 349, 847 (1999)