5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate(Also See: L375720)

• Catalog No.: M330135
• M. F.: C20H25CaN7O6
• M. W.: 499.5338
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S)-2-[(4-{[(2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid calcium
• IUPAC Traditional name: (2S)-2-[(4-{[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid calcium
• Synonyms: N5-Methyltetrahydrofolate Calcium Trihydrate; N-Methyltetrahydrofolate Calcium Trihydrate; Prefolic A; N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid Calcium Trihydrate; N5-MethyltetrahydropteroylglutamateCalcium Trihydrate; Metafolin

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >300°C (dec.)
• Solubility: Water
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA; reduces total serum homocysteine level in orthotopic liver transplant recipients.

REFERENCES

• Fassbender, K., et al.: Lancet, 353, 1586 (1999)
• Pruthi, J., et al.: Liver Transpl., 7, 811 (1999)
• Wu, L., et al.: Clin. Chim. Acta, 322, 21 (1999)
• Eisen, H., et al.: N. Engl. J. Med., 349, 847 (1999)