(1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate (Chloropretadalafil)

• Catalog No.: M330125
• CAS Number: 171489-59-1
• M. F.: C22H19ClN2O5
• M. W.: 426.84966
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: methyl (1R,3R)-1-(2H-1,3-benzodioxol-5-yl)-2-(2-chloroacetyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylate
• IUPAC Traditional name: methyl (1R,3R)-1-(2H-1,3-benzodioxol-5-yl)-2-(2-chloroacetyl)-1H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylate
• Synonyms: (1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester

DATABASE IDS

• CAS Number: 171489-59-1

PROPERTIES

• Apperance: Pale Yellow to Pale Orange Solid
• Melting Point: 215-218°C (dec.)
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

An intermediate in the synthesis of Tadalafil (T004500), which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.

REFERENCES

• Carrier, S., et al.: Can. J. Urol., 10(1)
• 12 (1)