6-Methyl Pergolide

• Catalog No.: M326070
• CAS Number: 57202-76-3
• M. F.: C17H22N2S
• M. W.: 286.43498
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2R,4R,7R)-6-methyl-4-[(methylsulfanyl)methyl]-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene
• IUPAC Traditional name: (2R,4R,7R)-6-methyl-4-[(methylsulfanyl)methyl]-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene
• Synonyms: (8β)-6-Methyl-8-[(methylthio)methyl]ergoline; LY 116467; LY 062

DATABASE IDS

• CAS Number: 57202-76-3

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: >256°C (dec.)
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Dimethylformamide
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Potent antagonist of 5-HT2A and 5-HT2B receptors on porcine cardiac valves, it also activates brain dopaminergic receptors and lowers cranial DOPAC levels in rats.

REFERENCES

• Fuller, R.W., et al.: Neuroendocrinol., 36, 285 (1983)
• Goernemann, T., et al.: J. Pharmacol. Exp. Ther., 324, 1136 (1983)